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Arnaud BUHOT

 

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 Arnaud BUHOT

Structure et Propriétés d'Architectures Moléculaires
Groupe Théorie

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  Functions

Since March 2002 : CEA research engineer

Since January 2007 : Head of the Theory Group


  Proposition de stage Master 2

Translocation de polymères à travers un nanopore

Contacts : A. Buhot ( ) et S. Mossa ( )

Puces à Aptamères

Contacts : Y. Roupioz ( ) et A. Buhot ( )


  Reserch interests

Theory of biochips (DNA or protein microarrays)

Biopolymer conformation

Polymer reptation

Soft Condensed Matter

Lectures on Numerical Simulations in Statistical Mechanics


  CV

Since Jan. 2007: Head of the Theory Group

Since March 2002: Research Engineer, SPrAM, INAC, CEA Grenoble

Jan. 2000 - Jan. 2002: Marie Curie Fellowship, Theoretical Physics, Oxford

Oct. 1999 - Jan. 2000: Postdoctoral Associate, Theoretical Physics, Oxford (EPSRC)

July 1998 - Sept. 1999: Research Associate, SPSMS, DRFMCCEA Grenoble (AMN)

May 1999: PhD in Physics, Université Joseph Fourier of Grenoble

Aug. 1997 - June 1998: Research Assistant (in lieu of Mulitary Duty), LPS, ENS Paris

Sept. 1996 - Jul 1997: Research Associate, SPSMS, DRFMC, CEA Grenoble (AMN)

Sept. 1992 - Aug. 1996: Student at the Ecole Normale Supérieure of Lyon


  Scientific publications

Viscosity and Renewal Times of Polymer Reptation Models

A. Buhot

Macromolecules 43, 9155-9159 (2010).

 

Salt Concentration Effects on Equilibrium Melting Curves from DNA Microarrays

J. Fuchs, J. B. fiche, A. Buhot, R. Calemczuk, T. Livache

Biophys. J. 99, 1886-1895 (2010).

 

Effects of formamide on the thermal stability of DNA duplexes on biochips

J. Fuchs, D. Dell'Atti, A. Buhot, R. Calemczuk, M. Mascini and T. Livache

Anal. Biochem. 397, 132-134 (2010)

 

SPR imaging for label-free multiplexed analyses of DNA N-glycosylase interactions with damaged DNA duplexes

 C. Corne, J.B. Fiche, D. Gasparutto, V. Cunin, E. Suraniti, A. Buhot, J. Fuchs, R. Calemczuk, T. Livache and A. Favier

Analyst 133, 1036-1045 (2008)

 

Point Mutation Detection by Surface Plasmon Resonance Imaging Coupled with a Temperature Scan Method in a Model System

 J. B. Fiche, J. Fuchs, A. Buhot, R. Calemczuk, and T. Livache

Anal. Chem. 80, 1049-1057 (2008)


Stretching of homopolymeric RNA reveals single-stranded helices and base-stacking

 Y. Seol, G. Skinner, K. Visscher, A. Buhot, and A. Halperin

Phys. Rev. Lett. 98, 158103 (2007)

Physics News Update, 829-2 (2007)

 

Temperature effects on DNA Chip Experiments from Surface Plasmon Resonance imaging: Isotherms and Melting Curves

 J. B. Fiche, A. Buhot, R. Calemczuk, and T. Livache

Biophys. J. 92, 935-946 (2007) 

Faculty of 1000 Biology evaluation


Hybridization at a Surface: The Role of Spacers in DNA Microarrays

 A. Halperin, A. Buhot and E. B. Zhulina

Lagnmuir 22, 11290-11304 (2006)  


On the Hybirdization Isotherms of DNA Microarrays: The Langmuir Model and its Extensions

 A. Halperin, A. Buhot and E. B. Zhulina

J. Phys. Condens. Matter 18, S463-S490 (2006)


Exact curvilinear diffusion coefficients in the repton model

 A. Buhot

 Eur. Phys. J. E 18, 239-244 (2005) 


Brush Effects on DNA Chips: Thermodynamics, Kinetics and Design Guidelines

 A. Halperin, A. Buhot and E. B. Zhulina

 Biophys. J. 89, 796-811 (2005)  


Cluster algorithm for nonadditive hard-core mixtures

A. Buhot

J. Chem. Phys. 122, 024105 (2005)

 

Hybridization Isotherms of DNA Microarrays and the Quantification of Mutation Studies

 A. Halperin, A. Buhot and E. B. Zhulina

 Clin. Chem. 50, 2254-2262 (2004)


Effects of stacking on the configurations and elasticity of single-stranded nucleic acids

 A. Buhot and A. Halperin

 Phys. Rev. E 70, 020902(R) (2004)


Sensitivity, specificity and the hybridization isotherms of DNA chips

 A. Halperin, A. Buhot and E. B. Zhulina  

Biophys. J. 86, 718-730 (2004)


Kovacs effect and fluctuation-dissipation relations in 1D kinetically constrained models

 A. Buhot

 J. Phys. A: Math. Gen. 36, 12367-12377 (2003)


Simple strong glass forming models: mean-field solution with activation

 A. Buhot, J. P. Garrahan and D. Sherrington

  J. Phys. A: Math. Gen. 36, 307-328 (2003)


Fluctuation-Dissipation Relations in the Activated Regime of Simple Strong-Glass Models

 A. Buhot and J. P. Garrahan

 Phys. Rev. Lett. 88, 225702 (2002)


Extension Behavior of Helicogenic Polypeptides

 A. Buhot and A. Halperin

Macromolecules 35, 3238-3252 (2002)


Crossover from fragile to strong glassy behaviour in the spin facilitated chain model

 A. Buhot and J. P. Garrahan

 J. Phys.: Condens. Matter 14, 1499-1507 (2002)


Glassy behaviour in simple kinetically constrained models: topological networks, lattice analogues and annihilation-diffusion

 D. Sherrington, L. Davison, A. Buhot and J. P. Garrahan

 J. Phys.: Condens. Matter 14, 1673-1682 (2002)


Rigorous Bounds to Retarded Learning

 A. Buhot, M. B. Gordon and J. P. Nadal

 Phys. Rev. Lett. 88, 099801 (2002)

 Comment to D. Herschkowitz and M. Opper, Phys. Rev. Lett. 86, 2174 (2001) 


Crossover from Fragile to Strong Glassy Behaviour in Kinetically Constrained Systems

 A. Buhot and J. P. Garrahan

 Phys. Rev. E 64, 021505 (2001)


Glassy behaviour in a 3-state spin model

L. Davison, D. Sherrington, J. P. Garrahan and A. Buhot

 J. Phys. A: Math. Gen. 34, 5147-5182 (2001)


Robust learning and generalization with Support Vector Machines

 A. Buhot and M. B. Gordon

 J. Phys. A: Math. Gen. 34, 4377-4388 (2001)


On the Helix-Coil transition in grafted chains

 A. Buhot and A. Halperin

 Europhys. Lett. 50, 756-761 (2000)


Storage capacity of a constructive learning algorithm

 A. Buhot and M. B. Gordon  

J. Phys. A: Math. Gen. 33, 1713-1727 (2000)


The Extension of Rod-Coil Multiblock Copolymers and the Effect of the Helix-Coil Transition

 A. Buhot and A. Halperin

Phys. Rev. Lett. 84, 2160-2163 (2000)


A reply to the Comment by A. A. Louis on  Phys. Rev. Lett. 82, 960 (1999) 

 A. Buhot

Phys. Rev. Lett. 84, 1841 (2000)


Phase separation in two-dimensional additive mixtures

 A. Buhot and W. Krauth

Phys. Rev. E 59, 2939-2941 (1999)


Packing fraction at the phase separation transition in hard-core mixtures

 A. Buhot

Phys. Rev. Lett. 82, 960-963 (1999)


Bayesian learning versus optimal learning

 M. B. Gordon and A. Buhot

Physica A 257, 85-98 (1998)


Numerical Solution of Hard-Core Mixtures

 A. Buhot and W. Krauth

Phys. Rev. Lett. 80, 3787-3790 (1998)

Phys. Rev. Focus 1, story 11, May 4, 1998


Phase transitions in optimal unsupervised learning

 A. Buhot and M. B. Gordon

Phys. Rev. E 57, 3326-3333 (1998)


Finite size scaling of the Bayesian perceptron

 A. Buhot, J.-M. Torres-Moreno and M. B. Gordon

Phys. Rev. E 55, 7434-7440 (1997)


Cost function and patterns distribution of the bayesian perceptron

 A. Buhot and M. B. Gordon

Phys. Lett. A228, 73-78 (1997) 


Precise study of some number fields and Galois actions occurring in conformal field theory

 E. Buffenoir, A. Coste, J. Lascoux, P. Degiovanni, A. Buhot  

Annales de l'institut Henri Poincaré (A) Physique théorique, 63, 41-79 (1995)

 

 Proceedings

Storage Capacity of the Tilinglike Learning Algorithm
A. Buhot and M. B. Gordon
Proceedings of the Conference Disordered and Complex Systems, pages 17-22,
King's College, London, July 2000

Statistical mechanics of support vector machines
A. Buhot and M. B. Gordon
Proceedings ESANN'99, 201-206 (1999)

Detection of two Gaussian clusters
A. Buhot and M. B. Gordon
Proceedings ESANN'99, 327-332 (1999)

Numerical simulations of an optimal algorithm for supervised learning
A. Buhot, J.-M. Torres-Moreno and M. B. Gordon
Proceedings ESANN'97, 151-156 (1997)